Blood and marrow transplant or BMT is used to treat a variety of disease but its basic purpose is the same. BMT is used to replace a malfunctioning or non-functioning bone marrow with a healthy, functioning marrow.
Before the transplant, patients undergo conditioning treatment with chemotherapy and/or total body irradiation (TBI). This conditioning treatment is used to eliminate the underlying disease, create space for the new marrow and prevent rejection of the new bone marrow. Following the conditioning treatment, patients undergo BMT to restore healthy bone marrow functioning.