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The Leukemia/Bone Marrow Transplant Program of BC

Hematology Dictionary
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I

Iatrogenic Disease
A disease produced as a consequence of medical or surgical treatment.

Idiopathic
Term applied to diseases to indicate that their cause is unknown.

Idiopathic Thrombocythaemia Purpura (ITP)
A rare disorder characterized by an acute shortage of platelets with resultant bruising and spontaneous bleeding. Anti-platelet antibodies are detectable in some cases. It may present in either an acute or a chronic form.

Immune Deficiency
Impaired ability of the body's defense mechanisms to combat infections by bacteria, viruses and fungi.

Immune Response
The reaction of the body to an antigen, for example an infectious agent, or to the tissues of another individual as in the rejection of an organ transplants.

Immunoglobulins
Proteins in the blood PLASMA, which function as antibodies and play an important part in controlling infections.

Immunosuppression
A treatment induced reduction in the body's defense mechanisms. Deliberate immunosuppression is a necessary part of the bone marrow transplant procedure to prevent graft versus host disease and graft rejection.

Induction Treatment
See remission induction

Intensification
Increasing the amount, number or combination of anti-cancer drugs given to a patient in an attempt to kill drug-resistant or residual leukemic cells.

Interferons
A family of proteins derived from human cells and involved in fighting viral infections. They are now available as products of genetic engineering for use in the treatment of a number of leukemia's and leukemia related diseases including hairy cell leukemia, chronic myeloid leukemia and aplastic anemia.

Intramuscular Injection
Injection into the muscle.

Intrathecal Injection
Injection of drugs into the spinal fluid to prevent or treat CNS leukemia or lymphoma.

Intravenous Infusion
The giving of antibiotics, blood products, anti-cancer drugs or nutrients into a patient's vein over a prolonged period of time.

Intravenous Injection
The giving of drugs into a vein through a syringe.

In Vitro
Literally meaning "in glass". Used to describe studies carried out on living cells or tissues grown in the laboratory.

In Vivo
In living tissue or in a whole organism.

 

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The information in this glossary is cited with permission from the Leukemia Research Foundation web site.

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